Ozempic and the similar drug Wegovy have been the subject of a lot of controversy and headlines. There is a global shortage of the drug, Elon Musk tweeted about it, and approval for adolescents to lose weight in the United States.
Semaglutide also aids the pancreas to produce insulin, which is what helps with type 2 diabetes. To use glucose (or blood sugar), our body requires insulin.
Semaglutide mimics the function of a natural hormone called GLP-1 (glucagonlike peptide-1), which is normally produced when our bodies detect nutrients in food. GLP-1 is part the signaling pathway that informs your body that you have eaten and prepares it for using the energy from your food.
GLP-1 secretion is triggered by macronutrients, which are simple sugars (monosaccharides), amino acids (from protein), and short-chain fatty acids (from fats).
These macronutrients are abundant in energy-dense food, which are foods high in fat and sugars with low water content. Evidence suggests that GLP-1 levels can increase by choosing foods rich in these nutrients.
It's not always easy for everyone. This system also means that we feel more hungry when we eat less and restrict our energy intake. For some people, the "set point" for hunger and weight might be different.
GLP-1 levels, especially after meals, have been shown to be lower in obese people, according to some studies. This could be due to decreased production or increased breakdown of GLP-1.It is possible that the receptors that detect it are less sensitive or have fewer receptors.
People will feel hungry again if they stop taking it. You may feel more hungry if you have lost a lot of weight quickly.
While many solutions to medication and diet problems focus on the individual, systemic changes that reduce the pressures and barriers that hinder healthy eating (like reducing work hours or raising the minimum wage) will be much more effective.
Remember that weight is only one aspect of your health. You can lose weight if you suppress your appetite and eat a high-quality diet low in micronutrients but you won't get more nourishment.
The old saying "Let food be your medicine" is catchy and often based in science. Drugs are intentionally chosen or designed to mimic hormones, compounds and other natural substances found in the body.
Science is useful for large populations. However, individual health care is important and should be based on the advice of qualified health care professionals. Your individual needs and situation can be addressed by dietitians and GPs.
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